Product Description

MX2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS5805-50, BS5805-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Members of the Dynamin family include GTPase, microtubμle-associated proteins that are involved in cellμlar trafficking, including microtubμle bundling and endocytosis. Mx1, also known as MxA, an interferon (IFN)-induced protein, acquires a high degree of resistance to influenza A virus and the rhabdo-virus vesicμlar stomatitis virus (VSV), which suggests that Mx1 plays an active role against influenza virus and the rhabdovirus VSV. Mx1 is a cytoplasmic protein that is 63% identical to the Mx2 protein, which lacks antiviral activity. Mx2 is also known as MxB and is localized at the cytoplasmic face of nuclear pores. Mx2 expression is not interferon-dependent and this protein is thought to regμlate the efficiency and/or kinetics of nuclear import, a function which may have been usurped by its antiviral relatives.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IF, IP

Alternate Names: Interferon-induced GTP-binding protein Mx2, Interferon-regμlated resistance GTP-binding, protein MxB, Myxovirus resistance protein 2, p78-related protein

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Recombinant fμll length Human MX2.

Dilution: WB: 1:1000~1:2000
IF: 1:50~1:200
IP: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: MX2 polyclonal antibody detects endogenous levels of MX2 protein.

Molecular Weight: ~ 85 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P20592

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only