MxB rabbit pAb - ES6295

MxB rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6295-50, ES6295-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008],

Alternate Name: MX2; Interferon-induced GTP-binding protein Mx2; Interferon-regulated resistance GTP-binding protein MxB; Myxovirus resistance protein 2; p78-related protein

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from the Internal region of human MxB.

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 82kD

Human Gene ID: 4600

Human SWISS Prot NO: P20592

Subcellular Location: Cytoplasm. Nucleus. Nucleus, nuclear pore complex. Localization to nuclear pores requires GTP-binding.

Research Use Only