Product Description

MYBPC3 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-63687-60, E-AB-63687-120, E-AB-63687-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: MYBPC3

Target Synonym: MYBPC3; CMD1MM; CMH4; FHC; LVNC10; MYBP-C; cardiac

Research Areas: Cardiovascular

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Mouse, Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q14896

Background: MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human MYBPC3 (NP_000247.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only