Product Description

MYBPC3 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27494-50, RA27494-100

Citations, Manuals and MSDS Available upon request.

Background: myosin binding protein C, cardiac (MYBPC3) Homo sapiens MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: MYBPC3; Myosin-binding protein C; cardiac-type; Cardiac MyBP-C; C-protein, cardiac muscle isoform

Applications: IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 4607

SWISS: Q14896

Source: Rabbit

Research Use Only