MYBPC3 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A12351-20, A12351-100
Citations, Manuals and MSDS Available upon request.
Background: MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3 is expressed exclusively in heart muscle and is a key regulator of cardiac contraction. Mutations in this gene are a frequent cause of familial hypertrophic cardiomyopathy.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Mouse, Rat
Protein Weight: 141kDa
Observed Molecular Weight: 170kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 4607
SWISS: Q14896
Alternate Names: FHC; CMH4; CMD1MM; LVNC10; MYBP-C; cMyBP-C; MYBPC3
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cell Biology Developmental Biology, Cytoskeleton, Actins, Cardiovascular, Heart, Contractility, Hypertrophy.
NCBI Alias: MYBPC3
Research Use Only