MYBPC3 Rabbit pAb - A12351

MYBPC3 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A12351-20, A12351-100

Citations, Manuals and MSDS Available upon request.

Background: MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3 is expressed exclusively in heart muscle and is a key regulator of cardiac contraction. Mutations in this gene are a frequent cause of familial hypertrophic cardiomyopathy.

Category: Polyclonal Antibodies

Applications: WB, IHC-P, ELISA

Cross-reactivity: Mouse, Rat

Protein Weight: 141kDa

Observed Molecular Weight: 170kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 4607

SWISS: Q14896

Alternate Names: FHC; CMH4; CMD1MM; LVNC10; MYBP-C; cMyBP-C; MYBPC3

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cell Biology Developmental Biology, Cytoskeleton, Actins, Cardiovascular, Heart, Contractility, Hypertrophy.

NCBI Alias: MYBPC3

Research Use Only