MYBPC3 rabbit pAb - ES8931

MYBPC3 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8931-50, ES8931-100

Citations, Manuals and MSDS Available upon request.

Background: MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008],

Alternate Name: Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform)

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human MYBPC3 Polyclonal

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 140kD

Human Gene ID: 4607

Human SWISS Prot NO: Q14896

Subcellular Location: cytosol, striated muscle myosin thick filament, C zone, sarcomere, A band,

Research Use Only