MYCN Polyclonal Antibody - BT-AP11605

MYCN Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP11605-20, BT-AP11605-50, BT-AP11605-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research Areas: Epigenetics and nuclear signaling; Cancer

Target Protein: MYCN

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: N-myc proto-oncogene protein

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P04198; Mouse: P03966; Rat: Q63379

Synonyms: N-myc proto-oncogene protein;Class E basic helix-loop-helix protein 37;bHLHe37

GeneID: Human: 4613

Research Use Only