Myd88 Mouse Monoclonal Antibody (2H12) - RA11719

Myd88 Mouse Monoclonal Antibody (2H12)

Size: 50μL, 100μL

Catalogue Numbers: RA11719-50, RA11719-100

Citations, Manuals and MSDS Available upon request.

Background: myeloid differentiation primary response 88 (MYD88) Homo sapiens This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.52% sodium azide.

Storage Instructions: -20°C/1 year

Applications: IHC

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 4615

Protein MW (KDa): 33

SWISS: Q99836

Source: Mouse

Research Use Only