MyD88 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA20572-50, RA20572-100
Citations, Manuals and MSDS Available upon request.
Background: myeloid differentiation primary response 88 (MYD88) Homo sapiens This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunocytochemistry: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Alternative Names: MYD88; Myeloid differentiation primary response protein MyD88
Applications: IF/ICC; WB; IHC-p; ELISA
Species Cross-Reactivity: Human; Mouse; Rat
GeneID (Human): 4615
Protein MW (KDa): 33
SWISS: Q99836
Source: Rabbit
Research Use Only