Product Description

MyD88 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA20572-50, RA20572-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: myeloid differentiation primary response 88 (MYD88) Homo sapiens This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IF/ICC, WB, IHC-p, ELISA

Alternate Names: MYD88, Myeloid differentiation primary response protein MyD88

Clonality: Polyclonal

Dilution: IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunocytochemistry: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight: 33

Protein Molecular Weight (kDa): 33

Storage: -20°C/1 year

Human Gene ID: 4615

Human SwissProt Number: Q99836

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only