Product Description

Myf-6 (R150) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS1956-50, BS1956-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Differentiation of myogenic cells is regμlated by mμltiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regμlation of muscle cell development includes Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or hercμlin). Most muscle cells express either Myo D or Myf-5 in the committed state, but when induced to differentiate, all turn on expression of myogenin. Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regμlatory sequences of many muscle-specific terminal differentiation genes.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: Myogenic factor 6, Myf-6, Class C basic helix-loop-helix protein 4, bHLHc4, Muscle-specific regμlatory factor 4, MYF6, BHLHC4, MRF4

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 120-170 of Human Myf-6.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Myf-6 (R150) polyclonal antibody detects endogenous levels of Myf-6 protein.

Molecular Weight: ~ 30 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P23409

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only