MYH Polyclonal Antibody - BT-AP05687

MYH Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05687-20, BT-AP05687-50, BT-AP05687-100

Citations, Manuals and MSDS Available upon request.

Background: MUTYH encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. A/G-specific adenine DNA glycosylase is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: MUTYH

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: MYH Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 60069

UniProt Accession: Human: Q9UIF7; Mouse: Q99P21; Rat: Q8R5G2

Synonyms: MUTYH; MYH; A/G-specific adenine DNA glycosylase; MutY homolog; hMYH

GeneID: Human: 4595; Mouse: 70603; Rat: 170841

Research Use Only