Product Description

MYH8 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61311-50, BS61311-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Actin is a highly conserved protein that is expressed in all eukaryotic cells. Actin filaments can form both stable and labile structures, and are crucial components of microvilli and the contractile apparatus of muscle cells. Myosin is a hexamer of two heavy chains (MHC) and four light chains (MLC) that interact with Actin to generate the force for diverse cellμlar movements, including cytokinesis, phagocytosis and muscle contraction. MYH3 (Myosin heavy chain 3), also known as muscle embryonic Myosin heavy chain or SMHCE, is a 1, 940 amino acid that localizes to the thick filaments of myofibrils. While highly expressed in fetal skeletal muscle, MYH3 is barely detectable in adμlt skeletal muscle. Defects in the gene encoding MYH3, which maps to human chromosome 17p13.1, are the cause of distal arthrogryposis type 2B (DA2B).

Category: Primary Antibody

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB

Alternate Names: Myosin-8, Myosin heavy chain 8, Myosin heavy chain, skeletal muscle, perinatal, MyHC-perinatal, MYH8

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center
region of human MYH8.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: MYH8 polyclonal antibody detects endogenous levels of MYH8 protein.

Molecular Weight: ~ 223 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P13535

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only