MYH9 Monoclonal Antibody-MB12155

MYH9 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB12155-50, MB12155-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P35579

Host: Rabbit

Reactivity: Human, Rat

Applications: WB, IHC-P, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20

Background: This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. [provided by RefSeq, Dec 2011]

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 227 kDa; Observed MW: 227 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of nonmuscle Myosin IIA in Hela, A549, HL-60, U2OS, C6 lysates using MYH9 antibody., Immunohistochemistry analysis of paraffin-embedded Human lung cancer using nonmuscle Myosin IIA antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: MHA; FTNS; EPSTS; BDPLT6; DFNA17; MATINS; NMMHCA; NMHC-II-A; NMMHC-IIA

Immunogen: A synthetic peptide of human non-muscle Myosin IIA

Conjugate: Unconjugated

Modification: Unmodified