Product Description

MYL6 Polyclonal Antibody

Catalogue Numbers: BS5807-50, BS5807-100

Sizes: 50µl, 100µl

Alternative Name: Myosin light polypeptide 6; 17 kDa myosin light chain; LC17; Myosin light chain 3; MLC-3; MLC3; Myosin light chain alkali 3; Myosin light chain A3; Smooth muscle and nonmuscle myosin light chain alkali 6

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P60660

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: The EF-hand domain is a twelve amino acid loop motif that is commonly found in proteins that participate in calcium-binding events within the cell. EF-hand domains generally exist in a pair that, together, form a stable four-helix bundle that enables the binding of calcium ions. MYL6 (myosin, light chain 6, alkali, smooth muscle and non-muscle), also known as ESMLC, LC17A, LC17B or MLC1SM, is a 151 amino acid protein that contains three EF-hand domains and exists as two alternatively spliced isoforms, designated smooth muscle (MLC3SM) and non-muscle (MLC3NM). Existing as an alkali light chain component of the hexameric Myosin complex, MYL6 participates in generating the force for cellular movements, thereby playing an important role in overall cellular function. The gene encoding MYL6 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MYL6 polyclonal antibody detects endogenous levels of MYL6 protein.

Bioworld Molecular Weight: ~ 17 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of MYL6 polyclonal antibody at 1:500 dilution
Lane 1: Hela cell lysate
Lane 2: sp2/0 cell lysate
Lane 3: H9C2 cell lysate

Immunogen: Synthetic peptide, corresponding to amino acids 101-146 of Human MYL6.

Conjugate: Unconjugated

Modification: Unmodified