MYL6B Polyclonal Antibody-BS71404

MYL6B Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS71404-50, BS71404-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P14649

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB 1:200 - 1:500

Background: MYL6B (Myosin light chain 6B) is a heavy chain regulator found in smooth muscle and non-muscle Myosin complexes. Three general classes of Myosin have been cloned: smooth muscle myosins, striated muscle myosins and non-muscle myosins. Contractile activity in smooth muscle is regulated by the calcium/calmodulin-dependent phosphorylation of myosin light chain by myosin light chain kinase. Myosin heavy chains are encoded by the MYH gene family and have Actin-activated ATPase activity which generates the motor function of Myosin. Although it contains three of the EF-hand domains common to Actin and other Myosin regulating proteins, MYL6B does not bind calcium during contraction. It is primarily found in a hexamer consisting of four light chains and two heavy chains.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MYL6B polyclonal antibody detects endogenous levels of MYL6B protein.

Bioworld Molecular Weight: ~ 23 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of extracts of various cells, using MYL6B antibody.

Alternative Name: MLC1SA; Myosin light chain 6B;

Immunogen: Recombinant protein of human MYL6B.

Conjugate: Unconjugated

Modification: Unmodified