Product Description

MYL9 (phospho-S19) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS4845-50, BS4845-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Myosin regμlatory light chains, including MRCL3 (also known as MRLC3 or MLCB), MRLC2 (also known as MLC-B) and MYL9 (also known as LC20, MLC2, MRLC1 or MYRL2), regμlate contraction in smooth muscle and non-muscle cells via phosphorylation by myosin light chain kinase (MLCK). Phosphorylation of myosin regμlatory light chains, catalyzed by MLCK in the presence of calcium and calmodμlin, increases the Actin-activated myosin ATPase activity, thereby regμlating the contractile activity. Myosin light chain is also located in striated skeletal muscle, where its function remains undefined.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Myosin regμlatory light polypeptide 9, 20 kDa myosin light chain, Short name=LC20, MLC-2C, Myosin RLC, Myosin regμlatory light chain 2, smooth muscle isoform, Myosin regμlatory light chain 9, Myosin regμlatory light chain MRLC1, MLC2, MRLC1, MYRL2, Myosin regμlatory light chain 12A, MLC-2B, Myosin RLC, Myosin regμlatory light chain 2, nonsarcomeric, Myosin regμlatory light chain MRLC3, MYL12A, MLCB, MRLC3, RLC

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylation

Immunogen: Synthetic phosphopeptide derived from human MYL9 around the phosphorylation site of Serine 19.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: p-MYL9 (S19) polyclonal antibody detects endogenous levels of MYL9 protein only when phosphorylated at Ser19. This antibody may detects endogenous levels of MYL12A protein only when phosphorylated at Ser18.

Molecular Weight: ~ 20 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P24844/P19105

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only