MYO15 rabbit pAb - ES9857

MYO15 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES9857-50, ES9857-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes an unconventional myosin. This protein differs from other myosins in that it has a long N-terminal extension preceding the conserved motor domain. Studies in mice suggest that this protein is necessary for actin organization in the hair cells of the cochlea. Mutations in this gene have been associated with profound, congenital, neurosensory, nonsyndromal deafness. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Read-through transcripts containing an upstream gene and this gene have been identified, but they are not thought to encode a fusion protein. Several alternatively spliced transcript variants have been described, but their full length sequences have not been determined. [provided by RefSeq, Jul 2008],

Source: Rabbit

Applications: IHC; IF

Dilution: IHC-p 1:50-300

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human protein . at AA range: 2990-3070

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 388kD

Human Gene ID: 51168

Human SWISS Prot NO: Q9UKN7

Subcellular Location: Cell projection, stereocilium. Cytoplasm, cytoskeleton. Localizes to stereocilium tips in cochlear and vestibular hair cells.

Research Use Only