Product Description

MYO1C Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Sizes: 50µl, 100µl

Catalogue Numbers: BS8595-50, BS8595-100

Swiss-Prot: O00159

Host: Rabbit

MYO1C Polyclonal Antibody-BS8595

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC, IF

All Applications: WB: 1:500~1:2000
IHC: 1:50~1:200
IF: 1:50~1:200

Background: This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: MYO1C polyclonal antibody detects endogenous levels of MYO1C protein.

Bioworld Molecular Weight: ~ 122kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of various cell lines, using MYO1C antibody., Immunofluorescence analysis of U20S cell using MYO1C antibody. Blue: DAPI for nuclear staining.

Alternative Name: Unconventional myosin-Ic; Myosin I beta; MMI-beta; MMIb; MYO1C

Immunogen: Recombinant full length Human MYO1C.

Modification: Unmodified

Conjugate: Unconjugated