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MYO1E Polyclonal Antibody - E-AB-90556

MYO1E Polyclonal Antibody - E-AB-90556

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MYO1E Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-90556-60, E-AB-90556-120, E-AB-90556-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: MYO1E

Target Synonym: MYO1E; FSGS6; HuncM-IC; MYO1C; myosin IE

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q12965

Background: This gene encodes a member of the nonmuscle class I myosins which are a subgroup of the unconventional myosin protein family. The unconventional myosin proteins function as actin-based molecular motors. Class I myosins are characterized by a head (motor) domain, a regulatory domain and a either a short or long tail domain. Among the class I myosins, this protein is distinguished by a long tail domain that is involved in crosslinking actin filaments. This protein localizes to the cytoplasm and may be involved in intracellular movement and membrane trafficking. Mutations in this gene are the cause of focal segmental glomerulosclerosis-6. This gene has been referred to as myosin IC in the literature but is distinct from the myosin IC gene located on chromosome 17.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human MYO1E

Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:1000-1:2000

Calculated MW: 127kDa

Observed MW: 127kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

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