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MYO5A Polyclonal Antibody - E-AB-62133

MYO5A Polyclonal Antibody - E-AB-62133

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MYO5A Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-62133-60, E-AB-62133-120, E-AB-62133-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: MYO5A

Target Synonym: MYO5A; GS1; MYH12; MYO5; MYR12; myosin VA

Research Areas: Metabolism,Neuroscience,Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9Y4I1

Background: This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.

Concentration: 1 mg/mL

Immunogen: Recombinant fusion protein of human MYO5A

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IF 1:50-1:100

Calculated MW: 212kDa/215kDa/218kDa

Observed MW: 240kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only