Myosin-11 Polyclonal Antibody-BS90908

Myosin-11 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90908-50, BS90908-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P35749(Human) Q63862(Rat)

Host: Rabbit

Reactivity: Human, Rat

Applications: WB, IHC, ICC/IF

All Applications: WB:1:500-1:1,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Background: Myosin is a highly conserved, ubiquitously expressed protein that interacts with Actin to generate the force for cellular movements. Conventional Myosins are hexameric proteins consisting of two heavy chain subunits, a pair of non-phosphorylatable light chain subunits and a pair of phosphorylatable light chain subunits, which is expressed by my calcium and calmodulin-dependent phosphorylation of Myosin light chain (MLC) Myosin heavy chains, encoded by the MYH gene family, contain Actin-activated ATPase activity which generates the motor function of Myosin. Myosin heavy chains were initially isolated from a human fetal skeletal muscle and are the major determinant in the Speed of contraction of skeletal muscle. Various isoforms of myosin heavy chains are differentially expressed depending on th E functional activity of the muscle.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Myosin-11 polyclonal antibody detects endogenous levels of Myosin-11 protein.

Bioworld Molecular Weight: 227 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: ICC staining smooth muscle Myosin heavy chain 11 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS., ICC staining smooth muscle Myosin heavy chain 11 in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Alternative Name: MYH11, KIAA0866, AAT4, DKFZp686D10126, DKFZp686D19237, FAA4, FLJ35232, MGC126726, MGC32963, MYH 11, MYH11, MYH11, Myosin 11, Myosin heavy chain 11, Myosin heavy chain 11 smooth muscle, Myosin heavy chain, Myosin heavy chain smooth muscle isoform, Myosin heavy polypeptide 11 smooth muscle, Myosin-11, SMHC, SMMHC, smooth muscle isoform, Smooth muscle myosin heavy chain 11 isoform SM2, Smooth muscle myosin heavy chain isoform SM2,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified