Myosin IIa (Phospho-Ser1943) Rabbit Polyclonal Antibody - BT-AP11469

Myosin IIa (Phospho-Ser1943) Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP11469-20, BT-AP11469-50, BT-AP11469-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions| including cytokinesis| cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17| Epstein syndrome| Alport syndrome with macrothrombocytopenia| Sebastian syndrome| Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.

Research Areas: Signal transduction

Target Protein: MYH9

Applications: WB

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Myosin IIa

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P35579; Mouse: Q8VDD5; Rat: Q62812

Synonyms: Myosin IIa;Ser1943; Myosin-9; Cellular myosin heavy chain; type A; Myosin heavy chain 9; Myosin heavy chain; non-muscle IIa; Non-muscle myosin heavy chain A; NMMHC-A; Non-muscle myosin heavy chain IIa; NMMHC II-a; NMMHC-IIA

GeneID: Human: 4627; Mouse: 17886; Rat: 25745

Research Use Only