Myosin Light Chain kinase Rabbit Monoclonal Antibody-BS40138

Myosin Light Chain kinase Rabbit Monoclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Sizes: 50µl, 100µl

Catalogue Numbers: BS40138-50, BS40138-100

Swiss-Prot: Q15746

Host: Rabbit

Myosin Light Chain kinase Rabbit Monoclonal Antibody-BS40138

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC ICC/IF FC

All Applications: WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50

Background: Regulates actin-myosin interaction through a non-kinase activity. Phosphorylates PTK2B/PYK2 and myosin light-chains. Involved in the inflammatory response (e.g. apoptosis, vascular permeability, leukocyte diapedesis), cell motility and morphology, airway hyperreactivity and other activities relevant to asthma. Required for tonic airway smooth muscle contraction that is necessary for physiological and asthmatic airway resistance.

Purification and Purity: Affinity-chromatography

Specificity: Myosin light chain kinase Antibody detects endogenous levels of total Myosin light chain kinase

Bioworld Molecular Weight: 200kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of myosin light chain kinase expression in HUVEC cell lysate., Immunohistochemical analysis of paraffin-embedded human colon, using Myosin light chain kinase Antibody.

Alternative Name: KMLS; KRP; MLCK; MYLK; myosin light chain kinase, smooth muscle and non-muscle isozymes; myosin light polypeptide kinase; telokin;

Immunogen: A synthesized peptide derived from human Myosin light chain kinase

Modification: Unmodified

Conjugate: Unconjugated