Myosin VIIa Polyclonal Antibody-BS60184

Myosin VIIa Polyclonal Antibody

Catalogue Numbers: BS60184-50, BS60184-100

Sizes: 50µl, 100µl

Alternative Name: Unconventional myosin-VIIa; MYO7A; USH1B

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q13402

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Myosins are molecular motors that move along filamentous Actin and influence cellular movements such as phagocytosis. There are seven classes of myosins in vertebrates, including Myosin II, and six unconventional Myosin classes, designated I, V, VI, VII, IX and X. Myosin VIIa is a plus end-directed motor that influences cilia formation and cell adhesion. Mutations in the human Myosin VIIa gene correlate with Usher syndrome, a disease characterized by congenital sensorineural deafness, vestibular dysfunction and retinitis pigmentosa.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Myosin VIIa polyclonal antibody detects endogenous levels of Myosin VIIa protein.

Bioworld Molecular Weight: ~ 254 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Myosin VIIa polyclonal antibody at 1:500 dilution
Lane 1: SKOVCAR whole cell lysate
Lane 2: HEK293T whole cell lysate

Immunogen: A synthetic peptide corresponding to residues in Human Myosin VIIa.

Conjugate: Unconjugated

Modification: Unmodified