MYOZ2 rabbit pAb - ES8545

MYOZ2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8545-50, ES8545-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder. [provided by RefSeq, Aug 2011],

Alternate Name: MYOZ2 C4orf5

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human MYOZ2. AA range:21-70

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 30kD

Human Gene ID: 51778

Human SWISS Prot NO: Q9NPC6

Subcellular Location: Cytoplasm, myofibril, sarcomere, Z line. Colocalizes with ACTN1 and PPP3CA at the Z-line of heart and skeletal muscle.

Research Use Only