Myp rabbit pAb - ES2881

Myp rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2881-50, ES2881-100

Citations, Manuals and MSDS Available upon request.

Background: NOL3 encodes an anti-apoptotic protein nucleolar protein 3 that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for NOL3.

Alternate Name: Myp; NOL3; Nop30; Nucleolar protein 3; apoptosis repressor ARC; apoptosis repressor with CARD; apoptosis repressor with caspase recruitment domain (CARD); muscle-enriched cytoplasmic protein; nucleolar protein of 30 kDa

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human ARC. AA range:159-208

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 28kD

Human Gene ID: 8996

Human SWISS Prot NO: O60936-2

Subcellular Location: [Isoform 1]: Nucleus, nucleolus. The SR-rich C-terminus mediates nuclear localization.; [Isoform 3]: Cytoplasm.; [Isoform 2]: Cytoplasm. Mitochondrion. Sarcoplasmic reticulum. Membrane; Lipid-anchor. Phosphorylation at Thr-149 results in translocation to mitochondria. Colocalized with mitochondria in response to oxidative stress.

Research Use Only