MYPR rabbit pAb - ES14583

MYPR rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES14583-50, ES14583-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant. [provided by RefSeq, Feb 2015],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human MYPR AA range: 206-256

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 5354

Human SWISS Prot NO: P60201

Subcellular Location: Cell membrane; Multi-pass membrane protein. Myelin membrane. Colocalizes with SIRT2 in internodal regions, at paranodal axoglial junction and Schmidt-Lanterman incisures of myelin sheat.

Research Use Only