MYPT1/2 (Phospho Ser668/Ser618) Rabbit Polyclonal Antibody - RA27549

MYPT1/2 (Phospho Ser668/Ser618) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27549-50, RA27549-100

Citations, Manuals and MSDS Available upon request.

Background: function:Regulates myosin phosphatase activity.,PTM:Phosphorylated by CIT (Rho-associated kinase) (By similarity) . Phosphorylated cooperatively by ROCK1 and CDC42BP on Thr-696. Phosphorylated on upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Contains 6 ANK repeats.,subcellular location:Along actomyosin filaments and stress fibers.,subunit:PP1 comprises a catalytic subunit, PPP1CA, PPP1CB or PPP1CC, and one or several targeting or regulatory subunits. PPP1R12A mediates binding to myosin. Interacts with ARHA and CIT (By similarity) . Binds PPP1R12B, ROCK1 and IL16.,

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:1000-2000 ELISA 1:5000-20000

Alternative Names: Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1;Myosin phosphatase target subunit 1;Protein phosphatase myosin-binding subunit)

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 4659

SWISS: O14974/O60237

Source: Rabbit

Research Use Only