Product Description

MYPT1/2 (Phospho Ser668/Ser618) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27549-50, RA27549-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:Regulates myosin phosphatase activity., PTM:Phosphorylated by CIT (Rho-associated kinase) (By similarity). Phosphorylated cooperatively by ROCK1 and CDC42BP on Thr-696. Phosphorylated on upon DNA damage, probably by ATM or ATR., sequence caution:Contaminating sequence. Potential poly-A sequence., similarity:Contains 6 ANK repeats., subcellular location:Along actomyosin filaments and stress fibers., subunit:PP1 comprises a catalytic subunit, PPP1CA, PPP1CB or PPP1CC, and one or several targeting or regulatory subunits. PPP1R12A mediates binding to myosin. Interacts with ARHA and CIT (By similarity). Binds PPP1R12B, ROCK1 and IL16.,

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Alternate Names: Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1;Myosin phosphatase target subunit 1;Protein phosphatase myosin-binding subunit)

Clonality: Polyclonal

Dilution: WB 1:1000-2000 ELISA 1:5000-20000

Storage: -20°C/1 year

Human Gene ID: 4659

Human SwissProt Number: O14974/O60237

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only