MYT1L rabbit pAb - ES14580

MYT1L rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES14580-50, ES14580-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the zinc finger superfamily of transcription factors. The encoded protein belongs to a novel class of cystein-cystein-histidine-cystein zinc finger proteins that function in the developing mammalian central nervous system. Forced expression of this gene in combination with the basic helix-loop-helix transcription factor NeuroD1 and the transcription factors POU class 3 homeobox 2 and achaete-scute family basic helix-loop-helix transcription factor 1 can convert fetal and postnatal human fibroblasts into induced neuronal cells, which are able to generate action potentials. Mutations in this gene have been associated with autosomal mental retardation-39 and autism spectrum disorder. Alternative splicing results in multiple variants. [provided by RefSeq, Aug 2016],

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human MYT1L AA range: 595-645

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 23040

Human SWISS Prot NO: Q9UL68

Subcellular Location: Nucleus. Chromosome. Preferentially binds to DNA binding sites that are in an open chromatin configuration.

Research Use Only