N-CoR Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: RA11736-50, RA11736-100
Citations, Manuals and MSDS Available upon request.
Condition: Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Store at: -20°C/1 year
Recommended Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification Technology: Affinity purification
Alternative Names: NCOR1, KIAA1047, Nuclear receptor corepressor 1, N-CoR, N-CoR1
Background: nuclear receptor corepressor 1 (NCOR1) Homo sapiens This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010],
Applications: WB, IHC-p, IF (paraffin section), ELISA
Species Cross-Reactivity: Human
GeneID (Human): 9611
SWISS: O75376
Source: Mouse
Immunogen: Purified recombinant fragment of N-CoR (aa1-192) expressed in E. Coli.
Category: Monoclonal
Research Use Only