N-CoR Polyclonal Antibody - BT-AP05814

N-CoR Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05814-20, BT-AP05814-50, BT-AP05814-100

Citations, Manuals and MSDS Available upon request.

Background: NCOR1 (nuclear receptor corepressor 1) encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. NCOR1 is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of NCOR1 are found on chromosomes 17 and 20.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: NCOR1

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: N-CoR Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 270210

UniProt Accession: Human: O75376; Mouse: Q60974

Synonyms: NCOR1; KIAA1047; Nuclear receptor corepressor 1; N-CoR; N-CoR1

GeneID: Human: 9611

Research Use Only