Product Description

N-Shc Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP06191-20, BT-AP06191-50, BT-AP06191-100

Citations, Manuals and MSDS Available upon request.

Background: SHC3 (SHC (Src Homology 2 Domain Containing) Transforming Protein 3) is a Protein Coding gene. Diseases associated with SHC3 include sclerosing hepatic carcinoma. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Bacterial invasion of epithelial cells. GO annotations related to this gene include protein kinase binding and receptor tyrosine kinase binding. An important paralog of this gene is SHC1.

Research Areas: Neuroscience

Target Protein: SHC3

Applications: IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: N-Shc Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 64056

UniProt Accession: Human: Q92529; Mouse: Q61120; Rat: O70143

Synonyms: SHC3; NSHC; SHCC; SHC-transforming protein 3; Neuronal Shc; N-Shc; Protein Rai; SHC-transforming protein C; Src homology 2 domain-containing-transforming protein C3; SH2 domain protein C3

GeneID: Human: 53358; Mouse: 20418

Research Use Only