N2DL2 rabbit pAb - ES11017

N2DL2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES11017-50, ES11017-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6. [provided by RefSeq, Jul 2015],

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from part region of human protein

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 27kD

Human Gene ID: 80328

Human SWISS Prot NO: Q9BZM5

Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Endoplasmic reticulum. Secreted. In CMV-infected fibroblasts, detected in the endoplasmic reticulum/cis-Golgi.

Research Use Only