Product Description

Na+ CP type α-pan (E1476) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS3558-50, BS3558-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Voltage-gated Na+ channels regμlate the permeability of excitable cells to sodium ions. During the propagation of an action potential, Na+ channels allow an influx of sodium ions, which rapidly depolarize the cell. The sodium channel protein is comprised of one α subunit and two β subunits. The Na+ CP type I and Na+ CP type IIα subunits are expressed in adμlt brain. Na+ CP type IIIα is expressed in embryonic brain, but not in adμlt brain. Na+ CP type IIIβ is a 215 amino acid, single-pass type I membrane protein that modμlates sodium channel gating kinetics and inactivates the channel opening more slowly than the Iβ subunit. It has an extracellμlar N-terminal domain, an N-terminal signal sequence, a single membrane-spanning region and a C-terminal cytoplasmic region.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC

Alternate Names: Sodium channel protein type 9 subunit alpha, Neuroendocrine sodium channel, hNE-Na, Peripheral sodium channel 1, PN1, Sodium channel protein type IX subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.7, SCN9A, NENA

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 1442-1496 of Human Na+ CP type α-pan.

Dilution: IHC:1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Na+ CP type α-pan (E1476) polyclonal antibody detects endogenous levels of Na+ CP type α-pan protein.

Molecular Weight: ~ 226 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q15858

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only