Product Description

Na+ CP type IIβ Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS5811-50, BS5811-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Voltage-gated sodium channels are selective ion channels that regμlate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarizes the cell. Na+ CP type IIβ (sodium channel, voltage-gated, typeII, β), also known as SCN2B, is a 215 amino acid single-pass type I membrane protein that plays a critical role in the expression and assembly of the heterotrimeric complex of the sodium channel and interacts with Tenascin-R to influence the clustering and regμlation of sodium channels at nodes of Ranvier. Expressed specifically in brain, Na+ CP type IIβ contains one Ig-like C2-type (immunoglobμlin-like) domain and is encoded by a gene that maps to human chromosome 11q23.3 and mouse chromosome 9 A5.2.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Sodium channel subunit beta-2, SCN2B, ORF Names: UNQ326/PRO386, Na+ CP typeIIβ

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 114-159 of Human Na+ CP type IIβ.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Na+ CP type IIβ polyclonal antibody detects endogenous levels of Na+ CP type IIβ protein.

Molecular Weight: ~ 24 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O60939

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only