Na+ CP type IIAlpha Polyclonal Antibody - BT-AP05752

Na+ CP type IIAlpha Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05752-20, BT-AP05752-50, BT-AP05752-100

Citations, Manuals and MSDS Available upon request.

Background: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. SCN2A encodes one member of the sodium channel alpha subunit gene family. It is heterogeneously expressed in the brain, and mutations in SCN2A have been linked to several seizure disorders. Several alternatively spliced transcript variants of SCN2A have been described, but the full-length nature of some of these variants has not been determined.

Research Areas: Neuroscience

Target Protein: SCN2A

Applications: IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Na+ CP type IIalpha Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 227975

UniProt Accession: Human: Q99250; Rat: P04775

Synonyms: SCN2A; NAC2; SCN2A1; SCN2A2; Sodium channel protein type 2 subunit alpha; HBSC II; Sodium channel protein brain II subunit alpha; Sodium channel protein type II subunit alpha; Voltage-gated sodium cha

GeneID: Human: 6326; Rat: 24766

Research Use Only