Na+/K+-ATPase α1 (phospho Ser16) rabbit pAb - ES6359

Na+/K+-ATPase α1 (phospho Ser16) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6359-50, ES6359-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],

Alternate Name: ATP1A1; Sodium/potassium-transporting ATPase subunit alpha-1; Na (+)/K (+) ATPase alpha-1 subunit; Sodium pump subunit alpha-1

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human ATPase around the phosphorylation site of Ser16. AA range:5-54

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 112kD

Human Gene ID: 476

Human SWISS Prot NO: P05023

Subcellular Location: Basolateral cell membrane; Multi-pass membrane protein. Cell membrane, sarcolemma; Multi-pass membrane protein. Cell projection, axon. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Research Use Only