Na+/K+-ATPase α2 rabbit pAb - ES6362

Na+/K+-ATPase α2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6362-50, ES6362-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood. [provided by RefSeq, Oct 2008],

Alternate Name: ATP1A2; KIAA0778; Sodium/potassium-transporting ATPase subunit alpha-2; Na (+)/K (+) ATPase alpha-2 subunit; Sodium pump subunit alpha-2

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human; Mouse; Rat; Monkey

Immunogen: The antiserum was produced against synthesized peptide derived from human ATP1A2. AA range:971-1020

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 112kD

Human Gene ID: 477

Human SWISS Prot NO: P50993

Subcellular Location: Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Research Use Only