Na+/K+-ATPaseAlpha 1 (Phospho-Tyr260) Polyclonal Antibody - BT-AP01189

Na+/K+-ATPaseAlpha 1 (Phospho-Tyr260) Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP01189-20, BT-AP01189-50, BT-AP01189-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Areas: Cancer; Metabolism; Neuroscience; Signal transduction; Tags and cell markers

Target Protein: ATP1A1

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Sodium/potassium-transporting ATPase subunit alpha-1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P05023; Mouse: Q8VDN2; Rat: P06685

Synonyms: Sodium/potassium-transporting ATPase subunit alpha-1 (Na(+)/K(+) ATPase alpha-1 subunit;EC 3.6.3.9;Sodium pump subunit alpha-1; Sodium/potassium-transporting ATPase subunit alpha-1; Na(+)/K(+) ATPase alpha-1 subunit; EC 3.6.3.9; Sodium pump subunit alpha-1

GeneID: Human: 476; Mouse: 11928; Rat: 24211

Research Use Only