Product Description

NACA1 (Phospho-S43) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS64574-50, BS64574-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticμlum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing resμlts in mμltiple transcript variants, but the fμll length nature of some of these variants, including those encoding very large proteins, has not been determined. There are mμltiple pseudogenes of this gene on different chromosomes.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: HSD48, NAC-alpha, NACA1, skNAC

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylation

Immunogen: Synthetic phosphopeptide derived from human NACA1 around the phosphorylation site of Serine 43.

Dilution: WB:1:500~1:1000 IHC:1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: NACA1 (Phospho-S43) polyclonal antibody detects endogenous levels of NACA1 protein only when phosphorylated at Ser43.

Molecular Weight: ~ 40 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q13765

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only