NACAD Polyclonal Antibody-BS5814

NACAD Polyclonal Antibody

Catalogue Numbers: BS5814-50, BS5814-100

Sizes: 50µl, 100µl

Alternative Name: NAC-alpha domain-containing protein 1; KIAA0363

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O15069

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: NACAD (NAC alpha domain containing) is a 1,562 amino acid protein that prevents non-secretory polypeptides from targeting the endoplasmic reticulum. Localizing to both the cytoplasm and nucleus, NACAD belongs to the NAC-alpha family and contains one NAC-A/B (NAC-alpha/beta) domain. The gene encoding NACAD maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: NACAD polyclonal antibody detects endogenous levels of NACAD protein.

Bioworld Molecular Weight: ~ 161 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of NACAD polyclonal antibody at 1:500 dilution
Lane 1: MCF-7 cell lysate
Lane 2: sp2/0 cell lysate
Lane 3: H9C2 cell lysate

Immunogen: Synthetic peptide, corresponding to amino acids 418-463 of Human NACAD.

Conjugate: Unconjugated

Modification: Unmodified