NADPH oxidase 4 (NOX4) Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A2201-20, A2201-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS) . The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 67kDa
Observed Molecular Weight: 67kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 50507
SWISS: Q9NPH5
Alternate Names: KOX; KOX-1; RENOX; NADPH oxidase 4 (NOX4)
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Endocrine Metabolism, Drug metabolism, Immunology Inflammation, Cardiovascular, Blood, Heart, Cardiovascular diseases, Heart disease.
NCBI Alias: NOX4
Research Use Only