NADPH oxidase 4 (NOX4) Rabbit pAb - A28280

NADPH oxidase 4 (NOX4) Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A28280-20, A28280-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS) . The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Mouse, Rat

Protein Weight: 67 kDa

Observed Molecular Weight: 67 kDa

Immunogen: Recombinant protein (or fragment) .

Species: Mouse

GeneID: 50490

SWISS: Q9JHI8

Alternate Names: KOX; KOX-1; RENOX

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:3000 - 1:12000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Signal Transduction, Cell Biology Developmental Biology, Endocrine Metabolism, Drug metabolism, Immunology Inflammation, Cardiovascular, Blood, Heart, Cardiovascular diseases, Heart disease.

NCBI Alias: NOX4

Research Use Only