NAIP Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-66987-60, E-AB-66987-120, E-AB-66987-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: NAIP
Target Synonym: NAIP; BIRC1; NLRB1; psiNAIP
Research Areas: Cancer, Cell Biology
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Rat
Application: WB
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q13075
Background: This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human NAIP (NP_075043.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Calculated MW: 159kDa
Observed MW: 160kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only