Product Description

NAIP Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27584-50, RA27584-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: NLR family apoptosis inhibitory protein (NAIP) Homo sapiens This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by Ref

Reactivity: Human, Mouse

Host: Rabbit

Applications: IHC-p, IF (paraffin section), ELISA

Alternate Names: Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein)

Clonality: Polyclonal

Dilution: IHC-p 1:50-200, ELISA 1:10000-20000

Storage: -20°C/1 year

Human Gene ID: 4671

Human SwissProt Number: Q13075

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only