NANOG Monoclonal Antibody - BT-MCA3280

NANOG Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3280-50, BT-MCA3280-100

Citations, Manuals and MSDS Available upon request.

Background: NANOG: Nanog homeobox. Entrez Protein NP_079141. Nanog is a divergent homeodomain protein that directs pluripotency and differentiation of undifferentiated embryonic stem cells. Nanog mRNA is present in pluripotent mouse and human cell lines, and absent from differentiated cells. Human Nanog protein shares 52% overall amino acid identity with the mouse protein and 85% identity in the homeodomain. Human Nanog maps to gene locus 12p13.31, whereas mouse Nanog maps to gene loci 6 F2. Murine embryonic Nanog expression is detected in the inner cell mass of the blastocyst. High levels of human Nanog expression were detected by Northern analysis in the undifferentiated N-Tera embryonal carcinoma cell line.

Research Areas: Epigenetics and nuclear signaling, Developmental biology, Stem cells, Cancer

Target Protein: NANOG

Applications: WB, ICC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 1E6C4

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: NANOG

Immunogen: Purified recombinant fragment of NANOG (aa20-166) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 35kDa

UniProt Accession: Q9H9S0

Synonyms: NANOG

GeneID: 79923

Research Use Only