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NANOS2 Polyclonal Antibody - E-AB-11419

NANOS2 Polyclonal Antibody - E-AB-11419

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NANOS2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-11419-60, E-AB-11419-120, E-AB-11419-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: NANOS2

Target Synonym: NANO2; Nanos homolog 2; Nanos homolog 2 Drosophila; NANOS2; NOS-2; NOS2

Research Areas: Epigenetics and Nuclear Signaling, Developmental Biology, Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P60321

Background: Nanos2, also known as NOS2, is a 138 amino acid protein that contains one nanos-type zinc finger. The nanos-type zinc finger is comprised of two C2HC motifs, each of which are capable of binding one molecule of zinc and each of which work in tandem to play essential roles in translational regulation events. Expressed specifically in male germ cells, Nanos2 is essential for spermatogonia formation and is required to support the self-renewal, proliferation and overall development of proximal germ cells. Additionally, Nanos2 is thought to regulate the translation of target mRNAs, possibly by associating with the 3’-UTR of select transcripts.

Concentration: 0.3 mg/mL

Immunogen: Recombinant protein of human NANOS2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only