Product Description

NaV1.7 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90912-50, BS90912-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q15858(Human) O08562(Rat)

Host: Rabbit

Reactivity: Human, Rat

Applications: ICC IHC

All Applications: ICC:1:50-1:200
IHC:1:50-1:200

Background: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-sensitive Na(+) channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain.

Purification and Purity: Peptide affinity purified.

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: NaV1.7 polyclonal antibody detects endogenous levels of NaV1.7 protein.

Bioworld Molecular Weight: 226 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: ICC staining NaV1.7 in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS., ICC staining NaV1.7 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Alternative Name: hNE-Na, PN1, SCN9A, NENA, ETHA, GEFSP7, hNE Na, hNE-Na, hNENa, NE NA, NENA, Neuroendocrine sodium channel, Peripheral sodium channel 1, PN1, Scn9a, SCN9A, Sodium channel protein type 9 subunit alpha, Sodium channel protein type IX subunit alpha, Sodium channel voltage gated type IX alpha, Sodium channel voltage gated type IX alpha polypeptide, Sodium channel voltage gated type IX alpha subunit, Voltage gated sodium channel alpha subunit Nav1.7, Voltage gated sodium channel subunit alpha Nav1, Voltage-gated sodium channel subunit alpha Nav1.7,

Immunogen: Peptide.

Conjugate: Unconjugated

Modification: Unmodified