Product Description

NBEA Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-12593-60, E-AB-12593-120, E-AB-12593-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: NBEA

Target Synonym: BCL8B; FLJ10197; KIAA1544; Lysosomal trafficking regulator 2; Lysosomal-trafficking regulator 2; LYST2; NBEA; NBEA; Neurobeachin; Protein BCL8B; Protein neurobeachin; RP11-270C18.1

Research Areas: Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q8NFP9

Background: This gene encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Brain-specific expression and coat protein-like membrane recruitment of a highly similar protein in mouse suggest an involvement in neuronal post-Golgi membrane traffic. Mutations in this gene may be associated with a form of autism. This gene and its expression are frequently disrupted in patients witHuman, Mouseultiple myeloma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants may exist, but their full-length nature has not been determined.

Concentration: 0.4 mg/mL

Immunogen: Synthetic peptide of human NBEA

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:25-1:100

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only