NBN Monoclonal Antibody - BT-MCA3273

NBN Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3273-50, BT-MCA3273-100

Citations, Manuals and MSDS Available upon request.

Background: Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: NBN

Applications: WB, IHC, ICC, FCM

Reactivity: Human, Rat

Clonality: Monoclonal

Clone ID: 7E4A2

Host: Mouse

Isotype: Mouse IgG2a

Full Product Name: NBN

Immunogen: Purified recombinant fragment of human NBN (AA: 467-615) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide.

Molecular Weight (Da): 85kDa

UniProt Accession: O60934

Synonyms: ATV, NBS, P95, NBS1, AT-V1, AT-V2

GeneID: 4683

Research Use Only